[HTML][HTML] Mitofusin-mediated contacts between mitochondria and peroxisomes regulate mitochondrial fusion

C Alsayyah, MK Singh, MA Morcillo-Parra… - PLoS …, 2024 - journals.plos.org
… , FA desaturation is triggered by the Δ9-fatty acid desaturase … that mitochondrial fusion is
governed by a balance betweenturnover is governed by the status of FA desaturation (Fig 3). …

[HTML][HTML] The regulation of mitochondrial homeostasis by the ubiquitin proteasome system

C Alsayyah, O Ozturk, L Cavellini… - … et Biophysica Acta (BBA …, 2020 - Elsevier
… that the UPS employs to regulate mitochondrial function and … mitochondrial fusion upon high
desaturation of fatty acids but … or whether they control turnover of the mitofusin through other …

Regulation of mitochondrial fusion by the Ubiquitin Proteasome System and physical contacts between mitochondria and peroxisomes in yeast Saccharomyces …

C Alsayyah - 2021 - theses.hal.science
… mitophagy is distinct from ubiquitin-dependent mitophagy, its … their biosynthesis and turnover
are tightly regulated. Membrane … and Mga2 is the fatty acid desaturase gene OLE1. Both …

A AAA ATPase Cdc48 with a cofactor Ubx2 facilitates ubiquitylation of a mitochondrial fusion-promoting factor Fzo1 for proteasomal degradation

S Nahar, A Chowdhury, T Ogura… - The journal of …, 2020 - academic.oup.com
turnover rate of Fzo1, but showed normal mitochondrial morphology. Thus, Ubp3 and Ubx2
seem independently to regulate mitochondrial … degraded in a ubiquitin-dependent manner (…

Mitochondrial fusion, fission, and mitophagy in cardiac diseases: challenges and therapeutic opportunities

DL Scheffer, AA Garcia, L Lee… - Antioxidants & Redox …, 2022 - liebertpub.com
… catabolism of metabolites (eg., fatty acids, glucose, and proteins) … their distinct role in
mitochondria fusion, trafficking, turnover, and … that regulate mitochondrial fission/fusion balance

Ceramides and mitochondrial homeostasis

S Ding, G Li, T Fu, T Zhang, X Lu, N Li, Q Geng - Cellular Signalling, 2024 - Elsevier
mitochondria are known to be the core factory of fatty acid catabolism, it raises the following
questions: do ceramides regulate mitochondrial … be either ubiquitin-dependent or ubiquitin-…

[HTML][HTML] Mitochondrial surveillance by Cdc48/p97: MAD vs. membrane fusion

M Escobar-Henriques, V Anton - International Journal of Molecular …, 2020 - mdpi.com
… , fatty acids, glucose, and heme, mitochondria provide an … Therefore, the exact role of mitofusin
turnover in mitophagy … MAD of mitofusins, Cdc48/p97 regulates mitochondrial dynamics …

The role of the proteasome in mitochondrial protein quality control

S Rödl, JM Herrmann - IUBMB life, 2023 - Wiley Online Library
… describe how the UPS controls mitochondrial proteins. Since most of … ubiquitin-dependent
balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion

Hepatic metabolic adaptation and adipose tissue expansion are altered in mice with steatohepatitis induced by high-fat high sucrose diet

G Baiges-Gaya, S Fernández-Arroyo… - The Journal of …, 2021 - Elsevier
fatty acids, monounsaturated fatty acids and polyunsaturated … and impaired hepatic
mitochondria turnover. In addition, the … with the inhibition of ubiquitin-dependent mitophagy. For …

Mrz1, a Novel Mitochondrial Outer Membrane RING Finger Protein, is Degraded Through the Ubiquitin–Proteasome Pathway in Schizosaccharomyces pombe

Z Liu, P Zhang, M Li, G Yang, Y Yu, H Lu, J Shang… - Current …, 2022 - Springer
… proteasomal turnover of mitofusins, inducing mitophagy and … In yeast, Mdm30 regulates
mitochondrial fusion by mediating Fzo1 … can be regulated by ubiquitin-dependent pathways [25]. …